Supplement laws in Alabama

(4)a. A synthetic controlled substance that is any material, mixture, or preparation that contains any quantity of the following chemical compounds, their salts, isomers and salts of isomers, unless specifically excepted, whenever the existence of these salts, isomers and salts of isomers is possible within the specific chemical designation or compound:
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87. 1,3-Dimethylamylamine, some trade or other names: (DMAA).
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367. Tianeptine.

The controlled substances listed in this section are included in Schedule II:
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e. Phenibut and any salt, sulfate, free acid, or other preparation of phenibut, and any salt, sulfate, free acid, compound, derivative, precursor, or preparation thereof that is chemically equivalent or identical with phenibut.

§ 119.1 Dietary supplements containing ephedrine alkaloids.
Dietary supplements containing ephedrine alkaloids present an unreasonable risk of illness or injury under conditions of use recommended or suggested in the labeling, or if no conditions of use are recommended or suggested in the labeling, under ordinary conditions of use. Therefore, dietary supplements containing ephedrine alkaloids are adulterated under section 402(f)(1)(A) of the Federal Food, Drug, and Cosmetic Act.

DMAA (1,3-dimethylamylamine) is an amphetamine derivative that has been marketed in sports performance and weight loss products, many of which are sold as dietary supplements. DMAA is not a dietary ingredient, and DMAA-containing products marketed as dietary supplements are illegal and their marketing violates the law.
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In 2019, the U.S. Court of Appeals for the Eleventh Circuit affirmed the lower court ruling, finding that DMAA is not a dietary ingredient and is not generally recognized as safe, and condemning and forfeiting the seized articles containing DMAA.

FDA considers tianeptine to be a substance that does not meet the statutory definition of a dietary ingredient and is an unsafe food additive.
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Because tianeptine does not qualify as a dietary ingredient, is not an approved food additive, is not GRAS, and does not meet any of the other listed exceptions to the dietary supplement definition, it is an unsafe food additive, and dietary supplements containing tianeptine are adulterated under the FD&C Act.

Phenibut is a substance that does not meet the statutory definition of a dietary ingredient.
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The products distributed by Chill6 allegedly contain, among other things, Phenibut HCl, which does not meet the statutory definition of a dietary ingredient and is an unsafe food additive.

Products consisting of or containing only pure or highly concentrated caffeine have been linked to at least two deaths in the United States in the last few years, and continue to present a significant public health threat. Many products that consist of only or primarily pure or highly concentrated caffeine are sold as dietary supplements. FDA considers some such products to be adulterated under section 402(f)(1)(A) of the Federal Food, Drug, and Cosmetic Act (FD&C Act) [21 U.S.C. § 342(f)(1)(A)], because they are dietary supplements that present a significant or unreasonable risk of illness or injury under the conditions of use recommended or suggested in the labeling or, if no conditions for use are suggested or recommended, under ordinary conditions of use.